Drug Manufacturing
From First Principles

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10x
Biologics yield
3x
Faster manufacturing cycles
<7 days
To validated expression data
What We Do

We design biologic drugs with optimal therapeutic and manufacturing properties from day one, eliminating costly delays in the manufacturing cycle and saving companies time and money.

1

Therapeutic Design

Generative models design biologics optimized for therapeutic efficacy from the start.

2

Manufacturability Engineering

Candidates are engineered for high manufacturing yields and developability, limiting manufacturing delays.

3

Developability Screening

In-silico assessment of thermal stability, viscosity, chemical liabilities, and purification compatibility.

4

Process-Ready Candidates

Leads delivered production-ready: potent, stable, non-immunogenic, and built for scalable manufacturing.

Features

Our models combine computational biology, structural modeling, and multi-objective optimization:built for modern biologics teams.

🧪

Structure-Aware Generation

Generate antibody sequences conditioned on 3D epitope structure using equivariant diffusion models trained on proprietary data.

Drug Property Prediction

Predict therapeutic and manufacturing properties across RNA, peptides, DNA, and antibody biologics.

🔍

Developability Scoring

Predict aggregation propensity, clearance, and expression yield to de-risk candidates before entering CMC.

📊

Interactive Dashboards

Visualize sequence landscapes, Pareto fronts, and campaign progress. Export reports for regulatory and partner discussions.

Publications & Press

Milestones and recognition from AbInitio's journey so far.

In the News

Therascript integrated into Fingerprint:now a finalist for the Alzheimer's Insights AI Prize

AbInitio's Therascript platform was incorporated into the Fingerprint consortium, a multi-institutional initiative leveraging agentic AI for Alzheimer's drug discovery. The team has advanced to the finals of the Alzheimer's Disease Data Initiative AI Prize.

Learn More 2026
Accelerator

Accepted into the MIT Heals Researcher 2 Entrepreneur (R2E) Accelerator

AbInitio was selected for MIT's R2E program, which provides funding, mentorship, and resources to translate breakthrough biomedical research into scalable ventures.

Learn More September 2025
Accelerator

Selected for the Fifty Years 5050 Program

AbInitio was chosen for the 5050 program by Fifty Years, a venture fund that backs founders building companies to solve the world's biggest problems through science and technology.

Learn More June 2025
Team

Deep domain expertise in computational biology, structural bioinformatics, and machine learning systems.

Daniel Mukasa

Founder & CEO
Caltech. Computational chemistry and machine learning for drug discovery. Daniel brings deep expertise in molecular modeling, quantum chemistry, and AI-driven therapeutic design to AbInitio.

Giovanni Traverso

Scientific Advisor
MIT. Gastroenterologist and biomedical engineer specializing in drug delivery and ingestible devices. Giovanni advises AbInitio on translational strategy and clinical applications.

Ready to accelerate your pipeline?

Join the pharma and biotech teams using Therascript to go from target to lead in weeks, not years.

Get in Touch